Di- 2-ethylhexyl phthalate dehp
WebJan 31, 1987 · Basis: Orally administered DEHP produced significant dose-related increases in liver tumor responses in rats and mice of both sexes. This may be a synopsis of the full weight-of-evidence narrative. … WebDi(2-ethylhexyl) phthalate (DEHP) by Tamie Nakajima PhD, Nancy B. Hopf PhD, and Paul A. Schulte PhD Citation for most recent IARC review IARC Monographs Vol 77, 2000. The use of di(2-ethylhexyl) phthalate (DEHP) has been modified since the last Monograph. An estimated 90% of DEHP is used as a plasticizer for PVC (Toxics Use Reduction Institute
Di- 2-ethylhexyl phthalate dehp
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WebDi-2-ethylhexyl phthalate (DEHP) exposure is widespread in the general population and previous research has suggested that it contains endocrine-disrupting properties that can adversely affect the reproductive health system. The objective of this study was to use the 2013-2016 National Health and Nu … WebDec 23, 2016 · Di(2-ethylhexyl) Phthalate CAS No. 117-81-7 Reasonably anticipated to be a human carcinogen ... DEHP is a phthalate ester that exists as a colorless oily liquid with a slight odor. It is slightly soluble in water and carbon tetrachlo-ride, miscible with mineral oil and hexane, and soluble in blood and ...
WebFeb 22, 2024 · Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal … WebApr 7, 2004 · Human exposure to di(2-ethylhexyl) phthalate (DEHP) occurs throughout life. Of particular concern is the exposure of fetuses, preterm infants, and babies because the …
Bis(2-ethylhexyl) phthalate (di-2-ethylhexyl phthalate, diethylhexyl phthalate, diisooctyl phthalate, DEHP; incorrectly — dioctyl phthalate, DIOP) is an organic compound with the formula C6H4(CO2C8H17)2. DEHP is the most common member of the class of phthalates, which are used as plasticizers. It is the … See more Di(2-ethylhexyl) phthalate is produced commercially by the reaction of excess 2-ethylhexanol with phthalic anhydride in the presence of an acid catalyst such as sulfuric acid or para-toluenesulfonic acid. It was first produced … See more DEHP is a component of many household items, including tablecloths, floor tiles, shower curtains, garden hoses, rainwear, dolls, toys, shoes, medical tubing, furniture upholstery, and swimming pool liners. DEHP is an indoor air pollutant in homes and schools. … See more Taiwan In October 2009, Consumers' Foundation, Taiwan (CFCT) published test results that found 5 out of the … See more • FDA Public Health Notification: PVC devices containing the plasticizer DEHP (archived page) • ATSDR ToxFAQs • CDC - NIOSH Pocket Guide to Chemical Hazards See more Due to its suitable properties and the low cost, DEHP is widely used as a plasticizer in manufacturing of articles made of PVC. Plastics may contain 1% to 40% of DEHP. It is also used as a See more Toxicity The acute toxicity of DEHP is low in animal models: 30 g/kg in rats (oral) and 24 g/kg in rabbits (dermal). … See more • Maradonna, Francesca; Evangelisti, Matteo; Gioacchini, Giorgia; et al. (2013). "Assay of vtg, ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect of Di-(2-ethylhexyl)-phthalate (DEHP) and phthalic acid (PA) in zebrafish primary … See more WebJan 31, 1987 · Basis: Orally administered DEHP produced significant dose-related increases in liver tumor responses in rats and mice of both sexes. This may be a synopsis of the full weight-of-evidence narrative. …
WebDi(2-ethylhexyl)phthalate (DEHP) is a man-made chemical. It is a colorless liquid with a slight odor. DEHP is added to plastics to make them flexible. It can be present in many common items such as wall coverings, floor tiles, upholstery, rainwear, packaging film …
WebDi(2-ethylhexyl)phthalate (DEHP) is a reproductive and developmental toxicant in animals and a suspected endocrine modulator in humans. There is widespread exposure to … flight washington dc to austinWebMar 4, 2024 · Di-2-ethylhexyl phthalate (DEHP) is a member of the class of phthalates, and the relationship between DEHP and POF has been investigated, showing that the … greater arnold business associationWebSafe Work Australia sets the workplace exposure standard for di- (2-Ethylhexyl) phthalate (DEHP) through the workplace exposure standards for airborne contaminants: Maximum eight hour time weighted average (TWA): 5 mg/m 3. Maximum short term exposure limit (STEL): 10 mg/m 3. These standards are only appropriate for use in workplaces and are … greater artesia foundationWebMar 29, 2024 · Di-(2-ethylhexyl) phthalate (DEHP) and mono-2-ethylhexyl phthalate (MEHP) can induce hepatic lipid metabolism disorders, while the molecular mechanism still remain unknown. We aim to explore the underlying mechanism of Notch signaling pathway on hepatic lipid accumulation induced by DEHP/MEHP. A total of 40 male wistar rats … flight washington dc to denverWebof the plasticizer di(2-ethylhexyl) phthalate (DEHP). The FDA warning came in the agency’s long-awaited safety assessment on DEHP. DEHP is used to soften PVC medical devices such as bags and tubing. DEHP has been shown to produce a wide range of adverse effects in experimental animals. The FDA concluded that exposures to patients … greater armadilloWebMar 4, 2024 · Di-2-ethylhexyl phthalate (DEHP) is a member of the class of phthalates, and the relationship between DEHP and POF has been investigated, showing that the mechanistic link between the two has been elucidated [11,12,13]. One of the previous studies demonstrated that DEHP disrupts estrous cyclicity and PI3K signaling . greater arlington prayer breakfastWebcontent="Di(2-ethylhexyl) phthalate (DEHP) is found in many plastics. Exposure to DEHP is generally very low. Increased exposures may come from intravenous fluids delivered … greater arnprior chamber of commerce